This is the question every single consumer is asking: "How Much Resveratrol Supplements Should You Take?" Numbers are everywhere. But, since the research of this substance is still considered to be on its childhood, a well-established dosage is yet to be defined.
In a laboratory test, mice fed with resveratrol supplements for 15 weeks had better treadmill endurance than the other population not provided the substance. The research workers say that the dose given was 400mg/kg of body weight. If it was a human weighing around 80kg, the dosage used for the mice would come to 32,000mg/day. But as fact dictates that humans have slower metabolic rates compared to mice, it would change to roughly 4,571mg/day, still a really large number and not proven safe by any study to human subjects.
As of today, the appropriate dosage is still a huge concern. However, some have already created a classification of the dosage being: Low, Moderate & High Dosages. The Low Dosage would range from 100 mg - 500 mg/day. Moderate Dosage, on the other hand, starts from 500 mg - 1,500 mg/day. Anything taken over 1,500 mg/day is considered High Dosage.
This however, is not followed by everybody. The human equivalent of a 20 mg/day of resveratrol made pronounced anti-aging gene-expression changes in laboratory mice and a pharmaceutical company actually encourages consumers to take resveratrol in that dosage. Another company claims that 15 mg taken twice a day with a 9-10 hour gap is necessary to get the maximum benefit. But, this is for the weight loss property of the supplement since the purpose of taking 2 separate dosages of 15 mg is to keep the Sirtuin 1 gene activated which aids in burning fat and converting them into useful energy.
Another firm asserts that large doses of their supplement, which they termed "mega doses," are necessary to obtain maximum effects. They can go from 500 mg to 1,000mg per dose, equivalent to Moderate Dosage, as mentioned earlier.
A volunteer study was made using those mega doses and unwanted effects were actually seen with the people taking such high doses. These effects, all reversible, include anemia, diarrhea, anxiety & over-thinning of the blood.
In choosing the dosage you think is right for you, it's important to know the amount of additives in the resveratrol supplementation at hand. If additives are there, a low dosage could be a great idea to save your self from nasty unwanted effects. Of course, this forbids you from getting maximum benefits from the compound so it's advisable to purchase only pure resveratrol-to give you the greatest possible benefits and at the same time, keep you from unwanted side effects.
The bioavailability of the supplement is also a factor to be thought about. This is the amount available for the body to be taken after it has undergone the passes required for it to be absorbed. Modern formulations of the supplement are enabling smaller doses to generate a higher bioavailability than ever before.
To be safe, some suggest a ramp-up period to the maximum dose. This means you start with a low dose and stick with it for a week or two until you're convinced that there're no reactions to the supplement. When done with the first two weeks or so, you can now increase the dosage about 20% and stick with that for another few weeks, and so on and so forth. Rest assured that resveratrol does not create major troubles. It is listed by the EPA as a non-toxic matter backed with many human trials.
As for the doubt "How Much Resveratrol Supplements Should You Take?" the answer is, inconclusive.
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